73231-34-2

  • Product Name:Florfenicol
  • Molecular Formula:C12H14Cl2FNO4S
  • Purity:99%
  • Molecular Weight:358.218
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Product Details;

CasNo: 73231-34-2

Molecular Formula: C12H14Cl2FNO4S

Appearance: White crystalline powder

Quality products make an important contribution to long-term revenue and profitability. Top Quality Chinese Manufacturer supply 73231-34-2 Florfenicol

1.What is the Florfenicol ?

Florfenicol can strongly interfere with the bacterial protein synthesis. It has a rapid absorption rate and is widely distributed in the body; it has long half-life without side effects such as aplastic anemia; not easy for bacteria to evolve drug resistance, and has no cross-resistance. Florfenicol can be used for the treatment of the systemic infection of livestock and aquatic animals, and has significant efficacy on treating respiratory infections and intestinal infections. Poultry: Escherichia coli disease, salmonellosis, infectious rhinitis, chronic respiratory disease, duck plague and other kinds of mixed infections caused by susceptible strains. Animals: Mixed infections such as infectious pleurisy, asthma, streptococcal disease, Escherichia coli disease, salmonellosis, contagious pleuropneumonia, enzootic pneumonia, paratyphoid piglets yellow white diarrhea, edema disease, atrophic rhinitis, lung epidemic, red white diarrhea piglets, and agalactia syndrome occurred in animals such as pigs, cows, and sheep. Crab: appendages ulcer disease, yellow gills, rotten gill, red legs and red fluorescent body inflammatory disease syndrome. Turtle: red neck disease, furunculosis, shot-hole disease, skin fester disease, inflammatory bowel disease, mumps, and bacterial sepsis. Frogs: cataract syndrome, ascites disease, sepsis, enteritis. Fish: enteritis disease, ascites disease, vibriosis, Edward coli disease. Eel: debonding septicemia (unique effect), Edward coli disease, red skin disease, inflammatory bowel disease.

Florfenicol is a fluorinated derivative of thiamphenicol. It is a protein synthesis inhibitor that inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(1R,2S)-2-(2,3-dimethylbenzoyl)amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol
108656-27-5

(1R,2S)-2-(2,3-dimethylbenzoyl)amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol

thiamphenicol
15318-45-3,90-91-5

thiamphenicol

Florfenicol
73231-34-2

Florfenicol

Conditions
Conditions Yield
With hydrogenchloride; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1.) 120 deg C, 5 h, 2.) 80 deg C, 2 h;
 
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(1R,2S)-2-amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol
76639-93-5,105182-37-4,118015-48-8

(1R,2S)-2-amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol

Florfenicol
73231-34-2

Florfenicol

Conditions
Conditions Yield
With triethylamine; In methanol; at 20 ℃;
96%
With triethylamine; In methanol; for 18h; Ambient temperature;
84%
With triethylamine; for 3.5h; Yield given; Heating;
 
With sodium carbonate; In methanol; at 60 - 65 ℃; for 2h;
 
With triethylamine; In methanol; at 20 - 25 ℃; for 12 - 16h; Product distribution / selectivity;
 
With triethylamine; In methanol; at 20 - 25 ℃;
 
With triethylamine; In methanol; for 3h; Inert atmosphere; Reflux;
1.04 g
With triethylamine; In methanol; at 45 ℃;
 
With triethylamine; In methanol; at 50 ℃; for 12h;
6.5 g
With triethylamine; In methanol; at 40 ℃; for 6h;
3.4 g
With triethylamine; In methanol; at 50 ℃; for 10h;
7.1 g

2.What is the CAS number for Florfenicol ?

The CAS number of Florfenicol is 73231-34-2.

More information of Florfenicol 73231-34-2 are:

CAS Number

73231-34-2

Density

1.451 g/cm3

Melting Point

153 °C

Boiling Point

617.5 °C at 760 mmHg

Flash Point

327.3 °C

Vapor Pressure

4.05E-12mmHg at 25°C

Refractive Index

1.575

HS CODE

29419090

PSA

91.85000

LogP

2.70550

Pka

10.73±0.46(Predicted)

3.What are another words for Florfenicol ?

Synonyms for Florfenicol 73231-34-2:Acetamide,2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-,[R-(R*,S*)]-;(-)-Florfenicol;Aquafen;Aquaflor;Floron;Nuflor;Sch 25298;Florfeniol;

4.What is the molecular formula of Florfenicol?

The chemical formula of  Florfenicol is C12H14Cl2FNO4S which containing 12 Carbon atoms,14 Hydrogen atoms,2 Chlorine atoms,1 Fluorine atoms,1 Nitrogen atoms,4 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of  Florfenicol is 358.218.

5.What is Florfenicol (73231-34-2) used for?

Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol . It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 μg/ml). Florfenicol is also active against clinical isolates of various bovine and porcine respiratory tract pathogens, including P. multocida, A. pleuropneumoniae, and B. bronchiseptica (MIC50s = 0.25-4 μg/ml). It inhibits peptidyl transferase activity in 70S ribosomes isolated from E. coli when used at a concentration of 1 mM. Formulations containing florfenicol have been used in the treatment of infectious respiratory disease in cattle.

InChI:InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)

Relevant articles related to Florfenicol:

Article

Source

Synthesis method of florfenicol

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, (2021/03/24)

Method for continuously preparing florfenicol based on micro-reaction system

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Paragraph 0053-0054; 0057-0061; 0065-0068; 0072-0075; ..., (2021/07/24)

6.Buy Florfenicol with the best price .

Shandong Longchang Pharmaceutical Co., Ltd is a quality supplier of Florfenicol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Florfenicol 73231-34-2.

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