41194-16-5
- Product Name:Apramycin sulfate
- Molecular Formula:C21H41N5O11.H2SO4
- Purity:99%
- Molecular Weight:637.66
Product Details;
CasNo: 41194-16-5
Molecular Formula: C21H41N5O11.H2SO4
High Quality Chinese Manufacturer supply 41194-16-5 Apramycin sulfate
- Molecular Formula:C21H41N5O11.H2SO4
- Molecular Weight:637.66
- Vapor Pressure:0mmHg at 25°C
- Boiling Point:823 °C at 760 mmHg
- Flash Point:451.6 °C
- PSA:366.62000
- LogP:-3.32920
Apramycin sulfate(Cas 41194-16-5) Usage
General Description |
Apramycin sulfate is a broad-spectrum aminoglycoside antibiotic used in veterinary medicine to treat bacterial infections in livestock, particularly in poultry. It works by inhibiting protein synthesis in bacteria, and is effective against a wide range of gram-negative and some gram-positive bacteria. Apramycin sulfate is not FDA-approved for use in humans, but has been used off-label in some cases to treat multi-drug resistant bacterial infections. It is typically administered through injection or added to animal feed. Like other aminoglycoside antibiotics, there is a risk of nephrotoxic and ototoxic side effects with prolonged use of apramycin sulfate. |
InChI:InChI=1/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6-,7-,8-,9+,10-,11-,12-,13-,14+,15+,16+,17+,18+,19-,20+,21+;/m1./s1
41194-16-5 Relevant articles
NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA
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Paragraph 0220; 0222; 0230; 0235, (2018/06/15)
A compound represented by the following ...
Methods and compositions for targeting DNA metabolic processes using aminoglycoside derivatives
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, (2008/06/13)
Protein targets for disease intervention...
Total synthesis of aminoglycoside antibiotics, apramycin and saccharocin (KA 5685)
Tatsuta,Akimoto,Takahashi,et al.
, p. 529 - 538 (2007/10/02)
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41194-16-5 Process route
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C74H81N7O19
- 37321-09-8,41194-16-5
apramycin
Conditions | Yield |
---|---|
With hydrogen; palladium; In 1,4-dioxane; water; acetic acid; for 2h; under 2206.5 Torr; Ambient temperature;
|
74% |
- 37321-09-8,41194-16-5
apramycin
Conditions | Yield |
---|---|
|
41194-16-5 Downstream products
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1247066-77-8
3-N-azidoacetyl-apramycin
-
82002-36-6
1,3,2',7',4-pentakis-N-(benzyloxycarbonyl)apramycin
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1365691-97-9
3,2'-bis-N-[(2S)-4-(benzyloxycarbonylamino)-2-hydroxybutyryl]apramycin
-
77967-91-0
1-N-(benzyloxycarbonyl)-apramycin
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